Celecoxib is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain, inflammation, and fever. Here's what you need to know about celecoxib:
Dosage:
For adults, the recommended dose is usually 100-200 mg once or twice daily, depending on the condition being treated.
For children, the dose is based on weight and should be determined by a healthcare professional.
In patients with liver or renal impairment, the dose may need to be adjusted. Consult with a healthcare professional for guidance.
Pregnancy and lactation:
Celecoxib should not be used during the third trimester of pregnancy as it may cause harm to the fetus.
It is not recommended during the first and second trimesters unless the benefits outweigh the risks.
Celecoxib passes into breast milk and may harm a nursing infant. Therefore, it is not recommended during lactation.
Indications:
Celecoxib is indicated for the treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute pain, and primary dysmenorrhea.
Advice to patients:
Celecoxib should be taken exactly as prescribed by a healthcare professional.
It should be taken with food or milk to reduce the risk of stomach upset.
Patients should not take more than the recommended dose or take it for longer than prescribed.
Patients should tell their healthcare professional if they have a history of heart disease, high blood pressure, liver or kidney disease, or stomach ulcers before taking celecoxib.
Administration:
Celecoxib is usually taken orally.
It is available in capsule form.
Pharmacokinetics:
Celecoxib is rapidly absorbed after oral administration.
Peak plasma concentrations are usually reached within 3 hours.
It is metabolized in the liver and excreted in the urine and feces.
Interactions:
Celecoxib may interact with other drugs, including blood thinners, corticosteroids, lithium, and methotrexate.
Patients should tell their healthcare professional about all the medications they are taking before taking celecoxib.
Adverse effects:
Common side effects of celecoxib include stomach upset, diarrhea, headache, and dizziness.
Rare but serious side effects may include heart attack, stroke, and gastrointestinal bleeding.
Patients should seek medical attention immediately if they experience chest pain, shortness of breath, weakness, slurred speech, or vision changes while taking celecoxib.
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