Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to relieve pain, inflammation, and fever. Here is some information on naproxen, including its dosage, indications, pharmacokinetics, interactions, and adverse effects
Dosage:
Adult Dosage: The recommended adult dose for naproxen is 250-500 mg twice daily or 375-500 mg once daily.
Children Dosage: The dosage for children varies based on the child's weight and age. A pediatrician should be consulted to determine the correct dosage.
Dosage in liver and renal impairment: The dose of naproxen may need to be adjusted in patients with liver or kidney impairment. It is important to consult a healthcare provider to determine the correct dosage.
Pregnancy and Lactation:
Pregnancy: Naproxen should not be used during the third trimester of pregnancy. It may cause complications for the fetus.
Lactation: Naproxen should not be used while breastfeeding. It can be transferred to the baby through breast milk.
Risk factors:
Naproxen should be used with caution in patients with a history of stomach ulcers or bleeding disorders.
Patients who are allergic to NSAIDs or aspirin should avoid taking naproxen.
Indications:
Naproxen is used to relieve pain, inflammation, and fever. It is commonly used to treat conditions such as arthritis, menstrual cramps, and headaches.
Advice to patient:
Naproxen should be taken with food or milk to reduce stomach upset.
Patients should not exceed the recommended dose of naproxen or take it for longer than prescribed.
Patients should avoid taking naproxen with other NSAIDs, aspirin, or blood thinners without consulting a healthcare provider.
Administration:
Naproxen is available in tablet, capsule, and liquid form. It should be taken orally with food or milk.
The tablets and capsules should be swallowed whole and should not be crushed or chewed.
Pharmacokinetics:
Naproxen is rapidly and completely absorbed from the gastrointestinal tract.
It has a half-life of 12-17 hours.
It is metabolized in the liver and excreted in the urine.
Interactions:
Naproxen can interact with other medications, including aspirin, blood thinners, corticosteroids, and some antidepressants. It is important to consult a healthcare provider before taking naproxen with any other medication.
Adverse effects:
The most common adverse effects of naproxen include stomach upset, nausea, vomiting, and headache.
Naproxen can also increase the risk of heart attack, stroke, and gastrointestinal bleeding. Patients who experience chest pain, shortness of breath, or black, tarry stools should seek medical attention immediately.
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